The new multi-tiered seriousness scale sometimes leads to over-reporting. Train clinical coders using the official AACT 4.2.4 AE Decision Tree (Appendix B of the specification).
Symptom: The software launches but disconnects after 10 minutes. This is common in classroom networks with aggressive firewall rules. Solution: Whitleist the following ports in your firewall: TCP 27000-27009 and TCP 2080. Also, ensure your system clock is synchronized with an NTP server—license validation is time-sensitive. aact 4.2.4
Set up automated validation rules. Example pseudocode: Mastering AACT 4
if record['AE_grade'] >= 3 and not record['serious_ae']:
raise ValidationError("AACT 4.2.4: Grade 3+ AE must be marked serious")
Map all legacy AACT 4.2.3 datasets to the new 4.2.4 schema. Tools like the AACT Migrator CLI (available from the official standards repository) can automate 80% of this process. Step 1: Inventory Existing Datasets Map all legacy AACT 4
